An Adult Case with Congenital Dilatation of Common Bile Duct : A Study on the Relationship Between Bile Acids and the Cause of Congenital Biliary Dilatation

先天性総胆管拡張症の一成人例 : 胆汁酸とその成因との関連についての検討

Harada Mitsuo

Takahashi Makoto

Kodama Motomu

Matsuyama Toshiya

Tanaka Tsuneo

Takeuchi Hitoshi

Kuramoto Taiju

Hoshita Takahiko

Ezaki Haruo

Hiroshima Journal of Medical Sciences

[PISSN] 0018-2052

[EISSN] 2433-7668

[NCID] AA00664312

Although it has been hypothesized that congenital dilataion of the common bile duct is caused by the reflux of pancreatic juice into the choledochus, the etiology of this disease is not yet established. To determine whether bile acids have relations with the cause of congenital biliary dilatation or haven't, we analyzed the choledochal bile in a patient with congenital biliary dilatation. The results showed that the level of lithocholic acid, which has been said to cause bile-stasis was within normal range and that unknown bile acids were not detected in this patient. Therefore, it has been con eluded that bile acids have no relations with the etiology of congenital biliary dilatation.

Congenital biliary dilatation

Bile acids

Lithocholic acid

Medical sciences [ 490 ]

eng

Hiroshima University School of Medicine

[ISSN] 0018-2052

[NCID] AA00664312

[PMID] 7182381