Analysis of Hepatic Failure Plasma by High Performance Gel-Chromatography

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Title ( eng )
Analysis of Hepatic Failure Plasma by High Performance Gel-Chromatography
Title ( jpn )
高速ゲルクロマトグラフィーによる肝不全血漿の分析
Creator
Kawanishi Hideki
Nishiki Masayuki
Sugiyama Masafumi
Kimura Sosuke
Tsuchiya Taro
Ezaki Haruo
Source Title
Hiroshima Journal of Medical Sciences
Volume 32
Issue 4
Start Page 451
End Page 454
Journal Identifire
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
Abstract
Plasma taken from hepatic failure rats induced by D-galactosamine was used to observe the variatiation in its chromatogram obtained by conducting a high performance gel-chromatography (TSK G2000SW used). The progress of hepatic failure caused distinct increase in the 12 abnormal peaks, especially peak b contained middle molecular weight substances, which showed a good correlation with the condition of progressing hepatic failure. Thus, the measurement of variation in gel-chromatogram, especially, in peak b, is effectives as a parameter of hepatic failure in progress.
Keywords
Hepatic failure
D-galactosamine
High performance gel-chromatography
Middle molecular substance
NDC
Medical sciences [ 490 ]
Language
eng
Resource Type departmental bulletin paper
Publisher
Hiroshima University School of Medicine
Date of Issued 1983-12
Publish Type Version of Record
Access Rights open access
Source Identifier
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 6678900