Experience with the Use of Mizoribine in Human Renal Transplantation

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Title ( eng )
Experience with the Use of Mizoribine in Human Renal Transplantation
Title ( jpn )
Mizoribine を用いたヒト腎移植の経験
Creator
Dohi Kiyohiko
Yahata Hiroshi
Fukuda Yasuhiko
Takenaka Masaharu
Tabe Yasuji
Ono Eiji
Fukuda Makoto
Omotehara Tamon
Eto Takaaki
Ezaki Haruo
Source Title
Hiroshima Journal of Medical Sciences
Volume 33
Issue 4
Start Page 809
End Page 812
Journal Identifire
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
Abstract
In addition to steroids and azathioprine, mizoribine was administered to 17 renal transplant recipients. In 9 of the 17, 16 acute rejections occurred. Seven of these 9 recovered without deterioration of graft function, but one lost the function. Mizoribine, which has been elucidated to produce a chronic rejection preventing effect fully when administered concurrently with steroids and azathioprine, proved to give a satisfactory immunosuppressive effect in a dose of 1 mg/kg/day when used simaltaneously with steroids and azathioprine.
Keywords
Renal transplantation
Mizoribine
Rejection
NDC
Medical sciences [ 490 ]
Language
eng
Resource Type departmental bulletin paper
Publisher
Hiroshima University School of Medicine
Date of Issued 1984-12
Publish Type Version of Record
Access Rights open access
Source Identifier
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 6398817