Increase in T. G-Cell Ratio in Renal Transplant Recipients and the Relationship to Complications

腎移植臨床例における T.G 陽性細胞の変動 : 合併症との関連性を中心に

Dohi Kiyohiko

Yahata Hiroshi

Fukuda Yasuhiko

Tabe Yasuji

Asahara Toshimasa

Ono Eiji

Ezaki Haruo

Hiroshima Journal of Medical Sciences

[PISSN] 0018-2052

[EISSN] 2433-7668

[NCID] AA00664312

The changes in lymphocyte subpopulations in renal transplant recipients were determined. Prior to immunosuppressive therapy, the subpopulation levels in the recipients were similar to those of healthy adults, but after administration of therapy, the T-cell ratio (%T) decreased, while the IgG-Fc receptor-bearing T-cell ratio (%T.G) increased. However, review of these changes in individual cases showed that among those with the same degree of decrease in %T, the %T.G increased only slightly in some, but markedly in others, thus, indicating that there was not necessarily an inverse correlation between the decrease in %T and increase in %T.G. Further, it is noted that when %T.G was markedly increased, the patient was susceptible to bacterial infection.

Transplantation

Immunosuppression

IgG-Fc receptor

Medical sciences [ 490 ]

eng

Hiroshima University School of Medicine

[ISSN] 0018-2052

[NCID] AA00664312

[PMID] 6384145