p26 : A Cell Surface Antigen Expressed Selectively by Hematopoietic Cells
Hiroshima Journal of Medical Sciences Volume 37 Issue 3
Page 133-137
published_at 1988-09
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| File | |
| Title ( eng ) |
p26 : A Cell Surface Antigen Expressed Selectively by Hematopoietic Cells
|
| Creator |
Takaishi Masatoshi
Fu Shu Man
|
| Source Title |
Hiroshima Journal of Medical Sciences
|
| Volume | 37 |
| Issue | 3 |
| Start Page | 133 |
| End Page | 137 |
| Journal Identifire |
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
|
| Abstract |
A monoclonal antibody (MoAb) H5 (IgG2b) was obtained by fusion between SP2/0, mouse myeloma cell line and spleen cells from BC3Fl mice immunized with HEL, a erythroleukemia cell line. MoAb H5 precipitated a 26 kilodalton (KD) polypeptide in reduced condition. It reacted with platelets, monocytes, eosinophiles, 13% of lymphocytes, thymocytes and colony-forming units-granulocyte/monocyte (CFU-GM), but not with neutrophiles, red blood cells (RBC) and burst-forming units-erythroid (BFU-E). It also stained T-lymphoid leukemia cell lines but not B cell lines. Thus this antigen was expressed selectively by both myeloid and lymphoid lineages.
|
| Keywords |
Monoclonal antibody
CFU-GM
Platelet
|
| NDC |
Medical sciences [ 490 ]
|
| Language |
eng
|
| Resource Type | departmental bulletin paper |
| Publisher |
Hiroshima University Medical Press
|
| Date of Issued | 1988-09 |
| Publish Type | Version of Record |
| Access Rights | open access |
| Source Identifier |
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 3248948
|
