The Effect of Bovine Brain Gangliosides on Essential Tremor

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Title ( eng )
The Effect of Bovine Brain Gangliosides on Essential Tremor
Creator
Ishizaki Fumiko
Harada Toshihide
Kito Shozo
Harada Akira
Saeki Masayumi
Nakamura Shigenobu
Source Title
Hiroshima Journal of Medical Sciences
Volume 40
Issue 2
Start Page 83
End Page 85
Journal Identifire
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
Abstract
We reported the case of a 74-year-old woman suffering from essential tremor for 20 years which was treated effectively with purified bovine brain gangliosides containing GM1, GD1a, GD1b and GT1b gangliosides. The trials of the treatment were conducted twice, 40 mg and 20 mg gangliosides per day respectively administered intramuscularly. Essential tremor dramatically improved with gangliosides on the second day of treatment, suggesting that the effect of gangliosides was not induced by neuronal sprouting or regeneration. It is speculated that a certain type of essential tremor is a reversible disease of membrane disorder.
Keywords
Gangliosides
Essential tremor
Therapeutic trials
Diabetic neuropathy
NDC
Medical sciences [ 490 ]
Language
eng
Resource Type departmental bulletin paper
Publisher
Hiroshima University Medical Press
Date of Issued 1991-06
Publish Type Version of Record
Access Rights open access
Source Identifier
[ISSN] 0018-2052
[NCID] AA00664312
[PMID] 1917560