Adjuvant Chemotherapy for Patients with Soft Tissue Sarcoma
Hiroshima Journal of Medical Sciences Volume 42 Issue 3
Page 109-115
published_at 1993-09
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| File | |
| Title ( eng ) |
Adjuvant Chemotherapy for Patients with Soft Tissue Sarcoma
|
| Creator |
Ozaki Toshifumi
Sugihara Shinsuke
Hamada Masanori
Nakagawa Yukou
Inoue Hajime
|
| Source Title |
Hiroshima Journal of Medical Sciences
|
| Volume | 42 |
| Issue | 3 |
| Start Page | 109 |
| End Page | 115 |
| Journal Identifire |
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
|
| Abstract |
Forty patients with soft tissue sarcoma (Enneking's stage I and II) were treated in our department between 1965 and 1992. We administered VACA regimen (composed of vincristine, actinomycin-D, cyclophosphamide, and doxorubicin) to 14 of 40 patients. Among 40 patients, the 5-year survival rate was 56% in 14 patients with chemotherapy and 39% in 26 without chemotherapy (p<0.02). In 32 patients of Stage II, the 5-year survival rate was 40% in 11 patients with chemotherapy and 31 % without chemotherapy (p<0.05). The improvement of the survival rate was due to delay in the development of lung metastases (chemotherapy group: 21.2 months after first visit, non-chemotherapy group: 9.4 months) and prolongation of the survival period after metastases (chemotherapy group: 26 months, non-chemotherapy group: 7.4 months).
|
| Keywords |
Soft tissue sarcoma
Chemotherapy
Survival
|
| NDC |
Medical sciences [ 490 ]
|
| Language |
eng
|
| Resource Type | departmental bulletin paper |
| Publisher |
Hiroshima University Medical Press
|
| Date of Issued | 1993-09 |
| Publish Type | Version of Record |
| Access Rights | open access |
| Source Identifier |
[ISSN] 0018-2052
[NCID] AA00664312
|
