Factors Affecting Postoperative Prognosis in the Solitary-nodule Type of Hepatocellular Carcinoma : Experience of 132 Cases in our Institute

Asahara Toshimasa

Dohi Kiyohiko

Katayama Koji

Itamoto Toshiyuki

Okamoto Yuzo

Nakahara Hideki

Ono Eiji

Sugino Keizo

Marubayashi Seiji

Yahata Hiroshi

Kitamoto Mikiya

Nakanishi Toshio

Azuma Kazuyoshi

Ito Katsuhide

Shimamoto Fumio

Hiroshima Journal of Medical Sciences

[PISSN] 0018-2052

[EISSN] 2433-7668

[NCID] AA00664312

A retrospective analysis of clinical and pathological factors was performed on 132 surgical cases with solitary-nodule type HCC in our hospital. The overall cancer-free survival rates after 1, 3 and 5 years were 82.2%, 42.3% and 26.5%, respectively. With univariate analysis, the significant prognostic factors for survival were tumor size, cancer cell infiltration of the fibrous capsule of the tumor (fc-inf), invasion into portal vein (vp), and intrahepatic metastasis (im), while significant prognostic factors for non-recurrence were tumor size, fc-inf, vp, im, Edmondson-Steiner's classification and perioperative blood transfusion. With multivariate analysis for recurrence, significant factors were vp, clinical stage (CS), and perioperative blood transfusion. Therefore, prognostic factors for long-term survival in surgical cases of HCC are thought to be good hepatic function, absence of portal invasion, and avoidance of perioperative blood transfusion if possible.

Hepatocellular carcinoma

Hepatectomy

Prognostic factor

Medical sciences [ 490 ]

eng

Hiroshima University Medical Press

[ISSN] 0018-2052

[NCID] AA00664312