Tumor Localization Studies and Surgical Treatment in Patients with Insulinoma
Hiroshima Journal of Medical Sciences Volume 47 Issue 2
Page 69-72
published_at 1998-06
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Title ( eng ) |
Tumor Localization Studies and Surgical Treatment in Patients with Insulinoma
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Creator |
Marubayashi Seiji
Tanaka Tsuneo
Shimizu Yohsuke
Matugu Yasuhiro
Fukuma Kazuyuki
Okada Kazuro
Ikeda Masahiro
Maeda Takashi
Oshiro Yoshio
Miura Yoshio
Dohi Kiyohiko
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Source Title |
Hiroshima Journal of Medical Sciences
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Volume | 47 |
Issue | 2 |
Start Page | 69 |
End Page | 72 |
Journal Identifire |
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
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Abstract |
In the present study, we retrospectively reviewed thirteen consecutive patients with insulinomas including 2 reoperations at our department for insulinomas, from the viewpoint of preoperative localization studies, surgery and long term follow-up. The results of the preoperative localization studies proved to be percutaneous transhepatic portal venous sampling (PTPVS) 6/7, angiography 8/15, ultrasonography (US) 6/11, endoscopic ultrasonography (EUS) 4/4, computed tomography (CT) 3/10, and magnetic resonance imaging (MRI) 2/2. The tumor was visualized by intraoperative ultrasonography CIUS) in 6 of 6 patients (100%). Six patients underwent enucleation, 6 patients underwent distal pancreatectomy, 2 patients underwent subtotal (80%) distal pancreatectomy, and one patient a pylorus preserving pancreaticoduodenectomy (PPPD). Two patients, one of whom belonged to the MEN-I group, underwent reoperations because they had multiple adenomas. The development of iatrogenic diabetes occurred in the case of 3 patients. These results suggest that the use of selected preoperative localization studies (PTPVS and probably EUS) may be very helpful for detecting insulinoma, and that IUS is an essential part of the operative exploration for insulinoma. Our data may further indicate the need for an aggressive surgical procedure in the case of multiple adenoma or insulinoma in MEN-I
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Keywords |
Insulinoma
Multiple endocrine neoplasia type-1
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NDC |
Medical sciences [ 490 ]
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Language |
eng
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Resource Type | departmental bulletin paper |
Publisher |
Hiroshima University Medical Press
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Date of Issued | 1998-06 |
Publish Type | Version of Record |
Access Rights | open access |
Source Identifier |
[ISSN] 0018-2052
[NCID] AA00664312
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