Two Cases of Hypothyroidism Complicated by Renal Dysfunction

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Title ( eng )
Two Cases of Hypothyroidism Complicated by Renal Dysfunction
Creator
Ogata Satoshi
Yorioka Noriaki
Tanji Chie
Asakimori Yukiteru
Ito Takafumi
Nishida Yoji
Taniguchi Yoshihiko
Yamakido Michio
Source Title
Hiroshima Journal of Medical Sciences
Volume 49
Issue 1
Start Page 93
End Page 96
Journal Identifire
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
Abstract
We report two patients in whom hypothyroidism was considered to cause renal dysfunction. Case 1 was a 65-year-old woman who stopped taking levothyroxine sodium for hypothyroidism. After 6 months, she developed proteinuria, edema, weight gain, and renal dysfunction. Renal biopsy revealed focal segmental proliferative glomerulonephritis. After re-administration of levothyroxine sodium, thyroid function and renal function both recovered. Case 2 was a 51-yearold man who presented with edema, difficulty in swallowing, muscular weakness, and fatigue. We diagnosed hypothyroidism, and focal segmental proliferative glomerulonephritis was revealed by renal biopsy. After administration of levothyroxine sodium, his symptoms resolved and his thyroid function and renal function both improved. Our experience suggests that hypothyroidism should be taken into consideration as one of the causes of renal dysfunction.
Keywords
Hypothyroidism
Renal dysfunction
Levothyroxine sodium
NDC
Medical sciences [ 490 ]
Language
eng
Resource Type departmental bulletin paper
Publisher
Hiroshima University Medical Press
Date of Issued 2000-03
Publish Type Version of Record
Access Rights open access
Source Identifier
[ISSN] 0018-2052
[NCID] AA00664312