EFFECT OF NEURAMINIDASE ON THE DURATION OF CONTACT WITH CON A IN LYMPHOCYTE STIMULATION
Hiroshima Journal of Medical Sciences Volume 30 Issue 2
Page 161-163
published_at 1981-06-10
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| File | |
| Title ( eng ) |
EFFECT OF NEURAMINIDASE ON THE DURATION OF CONTACT WITH CON A IN LYMPHOCYTE STIMULATION
|
| Title ( jpn ) |
リンパ球活性化におけるコンカナバリンAの接触時間に対するノイラミニダーゼの作用
|
| Creator |
Sakano Takashi
Kittaka Eishi
Hyodo Sumio
Horino Nobuko
Tanaka Yoshito
Usui Tomofusa
|
| Source Title |
Hiroshima Journal of Medical Sciences
|
| Volume | 30 |
| Issue | 2 |
| Start Page | 161 |
| End Page | 163 |
| Journal Identifire |
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
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| Abstract |
Neuraminidase-treatment greatly increased 3H-thymidine incorporation by human lymphocytes at lower concentrations of Con A. An irreversible sequence after 24 hr of incubation in the presence of the optimal concentration of Con A was found. However, at a suboptimal concantraiton of Con A, neuraminidase-treated lymphocytes exposed to Con A for 72 hr exhibited a greater magnitude of 3H-thymidine incorporation in contrast to the neuraminidase-treated lymphocytes exposed to Con A for 24 hr, indicating that the enancement effect of neuraminidase was not due to the increased binding of Con A to cell surfaces.
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| Descriptions |
This work was supported in part by Grant-in-Aid for Scientific Research (Project Nos. 544050 and 577401) from the Ministry of Education, Science and Culture of Japan.
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| NDC |
Medical sciences [ 490 ]
|
| Language |
eng
|
| Resource Type | departmental bulletin paper |
| Publisher |
Hiroshima University School of Medicine
|
| Date of Issued | 1981-06-10 |
| Publish Type | Version of Record |
| Access Rights | open access |
| Source Identifier |
[ISSN] 0018-2052
[NCID] AA00664312
|
