NATURAL KILLER (NK) ACTIVITY IN PATIENTS WITH CHRONIC GRANULOMATOUS DISEASE

Hiroshima Journal of Medical Sciences Volume 30 Issue 2 Page 135-139 published_at 1981-06-10
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Title ( eng )
NATURAL KILLER (NK) ACTIVITY IN PATIENTS WITH CHRONIC GRANULOMATOUS DISEASE
Title ( jpn )
慢性肉芽腫症患者のナチュラル・キラー(NK)活性について
Creator
Tanaka Yoshito
Sakano Takashi
Usui Tomofusa
Source Title
Hiroshima Journal of Medical Sciences
Volume 30
Issue 2
Start Page 135
End Page 139
Journal Identifire
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
Abstract
Natural killer (NK) activity against K 562 target cells was explored in 4 patients with chronic granulomatous disease (CGD). Although the NK activity of these patients was normal, the activity did not change after removal of monocytes from the effector cell population, contrary to normal adult controls.  

The possibility of a defect in the regulatory function of monocytes on NK activity in CGD patients is discussed.
Descriptions
This work was supported by a Research Grant (No. 544050) from the Ministry of Education, Science and Culture of Japan.
NDC
Medical sciences [ 490 ]
Language
eng
Resource Type departmental bulletin paper
Publisher
Hiroshima University School of Medicine
Date of Issued 1981-06-10
Publish Type Version of Record
Access Rights open access
Source Identifier
[ISSN] 0018-2052
[NCID] AA00664312