New Dopamine Agonist Pramipexole Improves Parkinsonism and Depression in Parkinson's Disease
Hiroshima Journal of Medical Sciences Volume 60 Issue 4
Page 79-82
published_at 2011-12
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Title ( eng ) |
New Dopamine Agonist Pramipexole Improves Parkinsonism and Depression in Parkinson's Disease
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Creator |
Harada Toshihide
Ishizaki Fumiko
Horie Nobuko
Nitta Yumiko
Yamada Tohru
Sasaki Tomohiro
Nagakane Tomoomi
Yasumatsu Yoshiteru
Nitta Kohsaku
Katsuoka Hiroyuki
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Source Title |
Hiroshima Journal of Medical Sciences
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Volume | 60 |
Issue | 4 |
Start Page | 79 |
End Page | 82 |
Journal Identifire |
[PISSN] 0018-2052
[EISSN] 2433-7668
[NCID] AA00664312
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Abstract |
Previous studies have shown that pramipexole might have the potential to improve depressive symptoms in patients with Parkinson's disease. To provide more evidence, in five Japanese patients at Hoehn & Yahr stage 1-3 we evaluated the Unified Parkinson's Disease Rating Scale (UPDRS), Hamilton Depression Rating Scale (HAMD) and Montgomery Asberg Depression Rating Scale (MADRS) at our hospital. After the pramipexole treatment, each total score of UPDRS, HAMD and MADRS significantly decreased compared with that before the treatment. Our data indicate that pramipexole improves depressive symptoms in patients with Parkinson's disease.
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Keywords |
Parkinson's disease
Depression
Pramipexole
UPDRS
MADRS
HAMD
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NDC |
Medical sciences [ 490 ]
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Language |
eng
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Resource Type | departmental bulletin paper |
Publisher |
Hiroshima University Medical Press
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Date of Issued | 2011-12 |
Rights |
(c) Hiroshima University Medical Press.
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Publish Type | Version of Record |
Access Rights | open access |
Source Identifier |
[ISSN] 0018-2052
[NCID] AA00664312
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