Tumor induction by monoenergetic neutrons in B6C3F1 mice

Journal of Radiation Research Volume 48 Issue 3 Page 205-210 published_at 2007
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Title ( eng )
Tumor induction by monoenergetic neutrons in B6C3F1 mice
Creator
Kashimoto Naoki
Kajimura Junko
Ishikawa Masayori
Source Title
Journal of Radiation Research
Volume 48
Issue 3
Start Page 205
End Page 210
Abstract
This study was undertaken to investigate induction of tumors by monoenergetic neutrons in B6C3F1 mice. Individual groups of 6 week-old animals of both sexes (about 30 mice/group) were exposed to 0.5 Gy of various monoenergetic neutrons (dose rate 0.5 cGy/min) and then observed for 13 months. The incidences of tumors (mainly liver neoplasms) in non-irradiated male and female controls were 11% and 0%, respectively. In the irradiated animals, the incidences were 53%, 50%, 60% and 43% in males, and 75%, 81%, 71%, and 85% in females, after 0.18, 0.32, 0.6 and 1.0 MeV neutron exposure, respectively. There were no significant differences in the tumor induction rate among the different energy groups
NDC
Medical sciences [ 490 ]
Language
eng
Resource Type journal article
Publisher
日本放射線影響学会
Date of Issued 2007
Rights
日本放射線影響学会, 本文データは学協会の許諾に基づきCiNiiから複製したものである
Publish Type Version of Record
Access Rights open access
Source Identifier
[ISSN] 0449-3060
[DOI] 10.1269/jrr.0614
[NCID] AA00705792
[NAID] 110006278195 isVersionOf
[DOI] http://dx.doi.org/10.1269/jrr.0614