Chemical analyses of hydroxyapatite formation on SAM surfaces modified with COOH, NH_2, CH_3, and OH functions

Hirata Isao

Akamatsu Mai

Fujii Eri

Poolthong Suchit

Okazaki Masayuki

Dental Materials Journal

Hydroxyapatite formation was examined at the surface of self-assembled monolayers (SAMs) modified with four functional groups, -COOH, -NH2, and -OH. For COOH-SAM and NH2-SAM, scanning electron spectroscopic observation showed that flake-like sheet crystals covered the whole wafer and small broccoli-like crystals were observed occasionally on the flake-like crystal base layer. For CH3-SAM and OH-SAM, no flake-like sheet crystals were observed; broccoli-like crystals were observed in a dispersed manner for CH3-SAM, but in localized spots for OH-SAM. X-ray diffraction patterns showed a strong apatite pattern oriented toward the c-axis direction for COOH-SAM. ESCA analysis revealed distinct Ca, P, O peaks for COOH-, NH2-, CH3-, and OH-SAM. Surface plasmon resonance (SPR) analysis indicated that during the supply of supersaturated calcium phosphate solution, the deposition of precipitates increased monotonically with time for COOH-SAM, increased slightly for NH2-SAM, but little increase in deposition was detected for CH3-SAM and OH-SAM.

Hydroxyapatite formation

SAM surfaces

Surface plasmon resonance

Medical sciences [ 490 ]

eng

日本歯科理工学会

Copyright (c) 2010 The Japanese Society for Dental Materials and Devices

[ISSN] 0287-4547

[DOI] 10.4012/dmj.2010-017

[NCID] AA10443149

[DOI] http://dx.doi.org/10.4012/dmj.2010-017