Histological and biomechanical study of impacted cancellous allografts with cement in the femur : a canine model

Archives of Orthopaedic and Trauma Surgery 128 巻 12 号 1357-1364 頁 2008-12 発行
アクセス数 : 749
ダウンロード数 : 224

今月のアクセス数 : 3
今月のダウンロード数 : 3
ファイル情報(添付)
タイトル ( eng )
Histological and biomechanical study of impacted cancellous allografts with cement in the femur : a canine model
作成者
Omoto Osamu
収録物名
Archives of Orthopaedic and Trauma Surgery
128
12
開始ページ 1357
終了ページ 1364
抄録
Introduction An experimental canine model was used for quantitative histological study using bone morphometry and biomechanical study on impacted cancellous allografting with cement in revision total hip arthroplasty.

Materials and methods The prosthesis had a collarless polished titanium alloy tapered stem with a head diameter of 15 mm. Twelve Beagle dogs were used. Cancellous bone grafts were obtained aseptically from the femoral condyles of other beagles. Histological examinations were performed up to 1 year after surgery. Biomechanical examinations were performed at 8 weeks after surgery.

Results The new bone formation proceeded from the proximal part to the distal site of the femur in the long axis as well as from the host cortical bone to the cement layer. Bone morphometry showed that the mineral apposition rate was higher in the proximal site of the femur than in the distal site at 8 weeks after surgery, but no significant differences were observed at other times. The bone formation rate was higher in the proximal site of the femur at 8 weeks after surgery, while it increased in the distal site at 16 weeks postoperatively but had decreased at 1 year after surgery significantly. The load test at 8 weeks after surgery showed that there was no significant difference at all sites attached strain gauge between impacted cancellous allograft group and control group.

Conclusion We concluded that biological replacement of the grafted bone by new bone settled at 1 year after surgery in this experimental model. However, the process was not completed.
著者キーワード
Impacted cancellous allograft
Revision THA
Histological study
Biomechanical study
NDC分類
医学 [ 490 ]
言語
英語
資源タイプ 学術雑誌論文
出版者
Springer
発行日 2008-12
権利情報
Copyright (c) 2009 Springer
出版タイプ Author’s Original(十分な品質であるとして、著者から正式な査読に提出される版)
アクセス権 オープンアクセス
収録物識別子
The original publication is available at www.springerlink.com
[ISSN] 0936-8051
[DOI] 10.1007/s00402-008-0732-5
[NCID] AA10738765
[DOI] http://dx.doi.org/10.1007/s00402-008-0732-5