Voltage-gated potassium channel antibodies associated limbic encephalitis in a patient with invasive thymoma
Journal of the Neurological Sciences Volume 250 Issue 1-2
Page 167-169
published_at 2006-12-01
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Title ( eng ) |
Voltage-gated potassium channel antibodies associated limbic encephalitis in a patient with invasive thymoma
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Creator |
Kohriyama Tatsuo
Arimura Kimiyoshi
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Source Title |
Journal of the Neurological Sciences
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Volume | 250 |
Issue | 1-2 |
Start Page | 167 |
End Page | 169 |
Abstract |
Recently, limbic encephalitis (LE) associated with Voltage-gated potassium channel antibody (VGKC-Ab) has been postulated as a new autoimmune disorder. Most previously reported cases of VGKC-Ab-associated LE were non-paraneoplastic, and reports of a paraneoplastic type are rare. Here we describe a 59-year-old woman with paraneoplastic VGKC-Ab-associated LE preceding the recurrence of invasive thymoma. There was a close temporal relationship between the clinical course and the changes of the VGKC-Ab titer. Unlike many of the non-paraneoplastic VGKC-Ab-associated LE cases, our cases showed the more extensive high intensity lesions on MRI and the absence of seizure and hyponatremia.
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Keywords |
Invasive thymoma
Limbic encephalitis
Voltage-gated potassium channel antibody
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NDC |
Medical sciences [ 490 ]
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Language |
eng
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Resource Type | journal article |
Publisher |
Elsevier
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Date of Issued | 2006-12-01 |
Rights |
Copyright (c) 2006 Elsevier Ltd.
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Publish Type | Author’s Original |
Access Rights | open access |
Source Identifier |
[ISSN] 0022-510X
[DOI] 10.1016/j.jns.2006.08.003
[NCID] AA00703265
[PMID] 17028029
[DOI] http://dx.doi.org/10.1016/j.jns.2006.08.003
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