Voltage-gated potassium channel antibodies associated limbic encephalitis in a patient with invasive thymoma

Journal of the Neurological Sciences Volume 250 Issue 1-2 Page 167-169 published_at 2006-12-01

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Title ( eng )	Voltage-gated potassium channel antibodies associated limbic encephalitis in a patient with invasive thymoma
Creator	Ohshita Tomohiko Kawakami Hideshi Maruyama Hirofumi Kohriyama Tatsuo Arimura Kimiyoshi Matsumoto Masayasu
Source Title	Journal of the Neurological Sciences
Volume	250
Issue	1-2
Start Page	167
End Page	169
Abstract	Recently, limbic encephalitis (LE) associated with Voltage-gated potassium channel antibody (VGKC-Ab) has been postulated as a new autoimmune disorder. Most previously reported cases of VGKC-Ab-associated LE were non-paraneoplastic, and reports of a paraneoplastic type are rare. Here we describe a 59-year-old woman with paraneoplastic VGKC-Ab-associated LE preceding the recurrence of invasive thymoma. There was a close temporal relationship between the clinical course and the changes of the VGKC-Ab titer. Unlike many of the non-paraneoplastic VGKC-Ab-associated LE cases, our cases showed the more extensive high intensity lesions on MRI and the absence of seizure and hyponatremia.
Keywords	Invasive thymoma Limbic encephalitis Voltage-gated potassium channel antibody
NDC	Medical sciences [ 490 ]
Language	eng
Resource Type	journal article
Publisher	Elsevier
Date of Issued	2006-12-01
Rights	Copyright (c) 2006 Elsevier Ltd.
Publish Type	Author’s Original
Access Rights	open access
Source Identifier	[ISSN] 0022-510X [DOI] 10.1016/j.jns.2006.08.003 [NCID] AA00703265 [PMID] 17028029 [DOI] http://dx.doi.org/10.1016/j.jns.2006.08.003 isVersionOf