高強度運動が血中Cu/Zn-SOD濃度とリンパ球中Cu/Zn-SODmRNA発現に及ぼす影響

Effects of high intense exercise on Cu/Zn-superoxide dismutase (Cu/Zn-SOD) concentration in blood, and Cu/Zn-SOD mRNA expression in lymphocytes

森河 亮

広島大学大学院教育学研究科紀要. 第二部, 文化教育開発関連領域

Bulletin of the Graduate School of Education, Hiroshima University. Part. II, Arts and science education

The purpose of the present study was to investigate the effects of high intense exercise on Cu/Zn-superoxide dismutase (Cu/Zn-SOD) concentration in human plasma and Cu/Zn-SOD mRNA expression in human lymphocytes. A single bout of 80% VOamax exercise induced a significant increase of the Cu/Zn-SOD concentration in plasma (p<0.05), but did not affect the expression of Cu/Zn-SODmRNA in lymphocytes. The expression of Cu/Zn-SODmRNA in lymphocytes was measured at first, third and last day of a training camp for five days. The expression of Cu/Zn-SODmRNA in lymphocytes in last day of the camp was significantly increased, compared with those in both first and third day of the camp (p<0.01, and p<0.05, respectively). The results obtained in this study suggest that the increase in plasma Cu/Zn-SOD concentration after acute bout of exercise may be occurred by mechanisms of release from tissues into bloodstream. The results of this study also suggest that repeating high intense exercise may promote the expression of Cu/Zn-SODmRNA in lymphocytes and Cu/Zn-SOD activity in lymphocytes.

Cu/Zn-SOD

リンパ球

運動

mRNA

Cu/Zn-SOD

lymphocyte

exercise

mRNA

生物科学・一般生物学 [ 460 ]

日本語

広島大学大学院教育学研究科

国立情報学研究所

[ISSN] 1346-5554

[NCID] AA11618725