Development of periodontal tissue regeneration therapy with new bioactive agents -- studies on brain-derived neurotrophic factor and ameloblastin peptide --
Hiroshima Conference on Education and Science in Dentistry, 2006 : the 40th Anniversary of Hiroshima University Faculty of Dentistry
Page 113-119
published_at 2006-01-08
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| File | |
| Title ( eng ) |
Development of periodontal tissue regeneration therapy with new bioactive agents -- studies on brain-derived neurotrophic factor and ameloblastin peptide --
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| Creator |
Kitagawa S.
Kitagawa M.
Shiba H.
Kawaguchi H.
Miyauchi M.
Tsuji K.
Uchida T.
Kurihara H.
Takata T.
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| Source Title |
Hiroshima Conference on Education and Science in Dentistry, 2006 : the 40th Anniversary of Hiroshima University Faculty of Dentistry
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| Start Page | 113 |
| End Page | 119 |
| Abstract |
To develop the periodontal regeneration therapy using bioactive agents, effects of two potential agents, brainderived neurotrophic factor (BDNF) and a synthetic peptide of ameloblastin on growth and differentiation of periodontal ligament cells in vitro and tissue healing in vivo. Both agents enhanced proliferation and mineralization of the periodontal ligament cells and induced periodontal tissue regeneration. We showed that BDNF and the ameloblastin peptide could be used as the promising medication to promote periodontal tissue regeneration.
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| Keywords |
periodontal tissue regeneration
brain-derived neurotrophic factor (BDNF)
ameloblastin
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| NDC |
Medical sciences [ 490 ]
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| Language |
eng
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| Resource Type | conference paper |
| Date of Issued | 2006-01-08 |
| Publish Type | Version of Record |
| Access Rights | open access |
| Source Identifier |
[URI] http://ir.lib.hiroshima-u.ac.jp/00014842
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