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Hiroshima Journal of Medical Sciences Volume 33 Issue 4
published_at 1984-12

Chromosome Analysis of Bone Marrow Fibroblast Colony-Forming Cells (CFU-F) in Heavily Exposed Atomic Bomb Survivors

近距離原爆被爆者における骨髄線維芽細胞（CFU-F）の染色体分析
Shigeta Chiharu
Tanaka Kimio
Kawakami Masahito
Ohkita Takeshi
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HiroshimaJMedSci_33_659.pdf
Abstract
A chromosome analysis was performed on cultured bone marrow fibroblasts (CFU-F) from two atomic bomb survivors exposed within 1 km of the hypocenter, whose estimated radiation dose is 357 rad and 365 rad respectively. In CFU-F of both cases, stable types of chromosome aberrations were detected. The rate of these chromosome aberrations related well to the chromosome aberration rate of peripheral T -lymphocytes of the same case. These findings suggest the possibility that chromosome aberration exists in somatic cells other than hematopoietic cells of heavily exposed atomic bomb survivors.
About This Article
Keywords
Chromosome aberration
Atomic bomb survivor
Fibroblast
CFU-F
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