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Hiroshima Journal of Medical Sciences Volume 31 Issue 1
published_at 1982-03-10
Ultrastructural Study of Human Natural Killer (NK) Cell
ヒトナチュラル・キラー（NK）細胞の電顕的考察
Kawaguchi Yoshinori
Kittaka Eishi
Tanaka Yoshito
Tanaka Takeo
Usui Tomofusa
Abstract
An electron microscopic study of human natural killer (NK) cells showed abundant cytoplasm and relatively large mitochondria. They also had various kinds of granules in their cytoplasm. The mode of binding to the tumor cell (K 562) was tight, and villi protruded from NK cells to the target cells. Some target cells were already lysed after incubation for 5 minutes at 4°C.
About This Article
Descriptions
This work was supported in parts by Grants-in-Aid for Scientific Research (Project Nos. 544050 and 56770468) from the Ministry of Education, Science and Culture of Japan.
Keywords
Natural killer cell
Transmission electron microscope
Other Article
PP. 45 - 50