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ID 49918
本文ファイル
著者
OKUSHIN, Sayuri
TAKAISHI, Masatoshi
TAKAHASHI, Naoko
OGAWA, Takahiko
KANAHARA, Koji
HAMAGUCHI, Naoki
HIRABAYASHI, Akira
WADA, Koji
YORIOKA, Noriaki
YAMAKIDO, Michio
キーワード
IgA nephropathy
Immunoglobulin production
Peripheral blood mononuclear cells
NDC
医学
抄録(英)
Immunoglobulin production by peripheral blood mononuclear cells of 27 patients of IgA nephropathy and 11 relatives was determined. In comparison with 15 healthy controls, no significant difference could be observed in both IgA nephropathy patients and relatives of the group not stimulated with PWM, but in the group stimulated with PWM a significant elevation in the production of IgA, IgG and IgM was seen in IgA nephropathy patients, while in the relatives a significant elevation in production of IgA and IgG was observed. It is speculated that immune complexes mainly IgA are the chief cause of development and progression of IgA nephropathy and that IgG and IgM are also involved. In also relatives, the presence of immunological abnormalities similar to those of IgA nephropathy patients is suggested.
掲載誌名
Hiroshima Journal of Medical Sciences
35巻
2号
開始ページ
177
終了ページ
182
出版年月日
1986-06
出版者
Hiroshima University School of Medicine
ISSN
0018-2052
NCID
PubMedID
言語
英語
NII資源タイプ
紀要論文
広大資料タイプ
学内刊行物(紀要等)
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
部局名
医歯薬学総合研究科
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