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ID 50006
本文ファイル
著者
YAMAMOTO, Masami
YAMAMOTO, Tetsuro
HATA, Jotaro
NAKAGAWA, Hitoshi
NAKATSUKA, Hirofumi
TAHARA, Eiichi
キーワード
Colorectal cancer
Atomic bomb survivors
Immunohistochemistry
NDC
医学
抄録(英)
In order to elucidate the biological characteristics of colorectal cancer among atomic bomb survivors in Hiroshima, a total of 159 cases of colorectal cancers comprising 73 cases in exposed atomic bomb survivors and 86 cases in non-exposed individuals were examined histologically and immunohistochemically for various functioning proteins. No statistical differences could be demonstrated in the incidence of various marker expressions of colorectal cancers between the exposed group and control group. However, comparison by the site of colorectal cancer showed that sigmoid colon cancers in the exposed group or high dose group showed a significantly higher frequency of glycoproteins such as α1-antichymotrypsin (ACT), secretory component (SC), α1-antitrypsin (AAT), and human chorionic gonadotropin (HCG) when compared with the control group. These results correlated well with the epidemiological data that the radiation effect on the incidence of colorectal cancer in atomic bomb survivors was most remarkable in the sigmoid colon.
内容記述
This study was supported in part by Grants in Aid for Cancer Research from the Ministry of Education, Science and Culture, Japan.
掲載誌名
Hiroshima Journal of Medical Sciences
36巻
4号
開始ページ
387
終了ページ
393
出版年月日
1987-12
出版者
Hiroshima University Medical Press
ISSN
0018-2052
NCID
PubMedID
言語
英語
NII資源タイプ
紀要論文
広大資料タイプ
学内刊行物(紀要等)
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
部局名
医歯薬学総合研究科
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