このエントリーをはてなブックマークに追加
ID 49914
本文ファイル
著者
KANATA, Suzue
キーワード
Chromosome abnormality
Mental retardation
Cerebral palsy
NDC
医学
抄録(英)
A cytogenetic study was made on heavy mentally retarded patients with cerebral palsy. The purpose of this study was to get a glimpse of the causes of mental retardation and cerebral palsy. As the results, chromosome abnormalities were found in 8.6% of the patients. By this study, it was revealed that chromosome abnormalities contribute significantly to the etiology of cerebral palsy.
The 58 cases examined in this study were admitted to National Sanatorium Kamo Hospital and Hiroshima Prefectural Handicapped Children's Hospital.
Chromosome slides were prepared in accordance with standard blood culture procedure. Karyotype analyses were made with the application of the conventional Giemsa staining and G-, C-, and Q-banding differential staining.
Of these 58 cases, 5 cases had abnormal karyotypes, showing an incidence of 8.6%. Of 5 abnormal karyotype cases, autosomal abnormalities were observed in 3 cases, and sex-chromosome abnormalities in 2 cases. And additional 4 cases had normal variations of no.1, 9, and Y chromosome. The clinical and cytogenetic findings of these patients were presented.
掲載誌名
Hiroshima Journal of Medical Sciences
35巻
2号
開始ページ
149
終了ページ
161
出版年月日
1986-06
出版者
Hiroshima University School of Medicine
ISSN
0018-2052
NCID
PubMedID
言語
英語
NII資源タイプ
紀要論文
広大資料タイプ
学内刊行物(紀要等)
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
部局名
医歯薬学総合研究科
他の一覧