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ID 49912
本文ファイル
著者
OHAMA, Koso
KUSUMI, Ichiro
FUJIWARA, Atsushi
キーワード
Induced abortus
Chromosome abnormality
Prenatal selection rate
Maternal age effect
NDC
医学
抄録(英)
A total of 1536 induced abortuses of less than 12 weeks gestation were cultured and 1355 successfully karyotyped. The study was divided into two periods: in the initial period 1224 abortion specimens were randomly collected, but in the later period 312 specimens of less than 8 weeks gestation or from women over 35 years of age were selectively collected. Eighty-six or 6.3% of the 1355 karyotyped specimens had chromosome abnormalities, and these included 61 trisomics, 9 monosomy X, 7 triploids, 5 double aneuploids, 2 tetraploids, one balanced translocation and one mosaic trisomy 22. Chromosomal abnormality rates by five-year maternal age intervals were 3.4 to 3.6% for women under 34 years of age, 9.3% for women aged 35-39 years and 23.0% for women over 40 years. Factors that may influence the prevalence of abnormal karyotypes in induced abortuses and prenatal selection rates of chromosome abnormalities compatible with livebirth are discussed.
掲載誌名
Hiroshima Journal of Medical Sciences
35巻
2号
開始ページ
135
終了ページ
141
出版年月日
1986-06
出版者
Hiroshima University School of Medicine
ISSN
0018-2052
NCID
PubMedID
言語
英語
NII資源タイプ
紀要論文
広大資料タイプ
学内刊行物(紀要等)
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
部局名
医歯薬学総合研究科
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