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ID 49911
本文ファイル
著者
YAMAKIDO, Michio
YANAGIDA, Jitsuro
ISHIOKA, Shinichi
MATSUZAKA, Shigeru
HOZAWA, Soichiro
TAKAISHI, Masatoshi
INAMIZU, Tsutomu
AKIYAMA, Mitoshi
NISHIMOTO, Yukio
キーワード
Poison gas workers
Lymphocyte subsets
Interleukin 2 production
NDC
医学
抄録(英)
A depression has been observed in phytohemagglutinin (PHA) response of lymphocytes, one of the functions of T cells, in former workers of the Okunojima poison gas factory (Poison gas workers) having a high risk of carcinogenesis. The authors in an attempt to delineate the mechanism of this depression measured lymphocyte subsets and interleukin 2 (IL-2) production of lymphocytes in these poison gas workers and compared the results with those obtained from age matched normal controls.
1) In comparison with normal controls it was observed with regard to lymphocyte subsets that both percentage and absolute number of Leu-2a+ cells in poison gas workers were significantly elevated and that both percentage and absolute number of Leu-7+ cells and Leu-3a/Leu-2a ratio were significantly depressed.
2) In comparison with normal controls IL-2 production of lymphocytes in poison gas workers showed a slightly low level, but the difference was not significant.
3) A significant positive correlation was demonstrated between PHA response, IL-2 production, and Leu-3a/Leu-2a ratio in poison gas workers.
掲載誌名
Hiroshima Journal of Medical Sciences
35巻
2号
開始ページ
127
終了ページ
134
出版年月日
1986-06
出版者
Hiroshima University School of Medicine
ISSN
0018-2052
NCID
PubMedID
言語
英語
NII資源タイプ
紀要論文
広大資料タイプ
学内刊行物(紀要等)
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
部局名
医歯薬学総合研究科
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