このエントリーをはてなブックマークに追加
ID 37735
本文ファイル
著者
Asahara, Toshimasa
Yano, Masatsugu
Fukuda, Saburo
Fukuda, Toshikatsu
Nakahara, Hideki
Katayama, Koji
Itamoto, Toshiyuki
Dohi, Kiyohiko
Nakanishi, Toshio
Kitamoto, Mikiya
Azuma, Kazuyoshi
Ito, Katsuhide
Moriwaki, Katsuyuki
Yuge, Osafumi
Shimamoto, Fumio
キーワード
Hepatocellular carcinoma
Brain metastasis
Hepatectomy
NDC
医学
抄録(英)
Brain metastasis from hepatocellular carcinoma (HCC) is a rare, yet perplexing problem in patients with cancer. We report on 5 patients with metastasis of HCC to the brain after radical hepatectomy. Intrahepatic recurrence occurred in 3 patients, and distant metastasis to sites other than the brain was observed in 3 patients (lung, 2; bone, 1). The symptoms for brain metastasis included headache, hemiparesis, and vomiting. Hemorrhage was found in 4 of 5 patients. All patients had a single nodular lesion in the brain. The alpha-fetoprotein levels were more than 10,000 ng/ml in 4 patients. Two patients underwent surgical resection, 1 received cranial irradiation, and 2 were administered corticosteroids. The interval between diagnosis of the primary cancer and detection of brain metastasis ranged from 2 to 54 months. The mean survival period was only 3 months after diagnosis of brain metastasis. All 5 patients died of neurologic causes. Because no effective treatment for brain metastasis from HCC is available, further study is needed.
掲載誌名
Hiroshima Journal of Medical Sciences
48巻
3号
開始ページ
91
終了ページ
94
出版年月日
1999-09
出版者
Hiroshima University Medical Press
ISSN
0018-2052
NCID
言語
英語
NII資源タイプ
紀要論文
広大資料タイプ
学内刊行物(紀要等)
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
部局名
医歯薬学総合研究科
病院
他の一覧