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ID 31175
本文ファイル
著者
Kubo, Nanami
Myojin, Yuki
Shimamoto, Fumio
Kashimoto, Naoki
Kyo, Eikai
キーワード
radiation protection
crypt survival
survival
Ganoderma luciduml (Rei-shi) mycelia
Agaricus blazei
B6C3F1 mouse
NDC
医学
抄録(英)
Radioprotective effects of a water-soluble extracts from cultured medium of Ganoderma lucidum (Rei-shi) mycelia (designed as MAK) and Agaricus blazei (Agaricus) against the shortening of survival time or the injury of crypt by X-irradiation were investigated in male B6C3F1 mice. MAK and Agaricus at three different doses were mixed into basal diet into biscuits at 5, 2.5 and 1.25% and administered from 1 week before irradiation. MAK (5% group) significantly prolonged animal survival as compared with basal diet group (control group) after 7 Gy of X-ray irradiation at a dose rate of 2 Gy min-1. At doses of 8, 10 and 12 Gy X-irradiation at a dose rate of 4 Gy min-1 MAK (5% group) significantly increased crypt survival as compared to other groups. These results suggest that MAK can act as a radioprotective agent.
掲載誌名
International Journal of Molecular Medicine
15巻
3号
開始ページ
401
終了ページ
406
出版年月日
2005-03
出版者
Spandidos Publications Ltd.
ISSN
1107-3756
NCID
言語
英語
NII資源タイプ
学術雑誌論文
広大資料タイプ
学術雑誌論文
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
権利情報
Copyright (c) 2005 Spandidos Publications Ltd.
部局名
原爆放射線医科学研究所