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ID 49781
本文ファイル
著者
MORIOKA, Takehiko 病院(医)
TOISHIGAWA, Kayo
KAWASE, Takakazu 原爆放射線医科学研究所 広大研究者総覧
FUKUSHIMA, Noriyasu 原爆放射線医科学研究所 広大研究者総覧
ICHINOHE, Tatsuo 原爆放射線医科学研究所 広大研究者総覧
キーワード
Streptococcus gallolyticus ssp. pasteurianus
febrile neutropenia
malignant lymphoma
抄録(英)
Background: Streptococcus gallolyticus ssp. pasteurianus is a commensal bacterium of the alimentary tract in humans and animals. This microorganism not only causes sepsis, endocarditis, and meningitis but is also associated with colorectal tumors. We report herein a rare case of S. gallolyticus ssp. pasteurianus bacteremia in a patient with concomitant colon cancer and aggressive malignant lymphoma during the neutropenic period after chemotherapy against lymphoma.
Case presentation: A 79-year-old man was found to have an adenoma in the ascending colon, and endoscopic mucosal resection (EMR) was planned to remove the lesion. However, he was diagnosed with diffuse large B-cell lymphoma during the pre-operation examination. The EMR was postponed, and he received rituximab, cyclophosphamide, etoposide, vincristine, and prednisolone (R-CEOP). He had a neutropenic fever with positive blood cultures for S. gallolyticus ssp. pasteurianus during the first course of R-CEOP. He improved as soon as cefepime was administered. Bacteremia did not recur thereafter, and he underwent EMR after completing six cycles of R-CEOP. The histological diagnosis of the colon tumor was well-differentiated adenocarcinoma in adenoma. Streptococcus gallolyticus ssp. pasteurianus was not detected in the culture of the resected tissue.
Conclusion: Although there have been few reports of bloodstream infection due to S. gallolyticus ssp. pasteurianus in patients with hematological malignancies undergoing cytotoxic chemotherapy, physicians should investigate the presence of coexisting colorectal tumors when this bacterium is isolated from blood cultures.
掲載誌名
Hiroshima Journal of Medical Sciences
69巻
2号
開始ページ
47
終了ページ
50
出版年月日
2020-06-30
出版者
Hiroshima University Medical Press
ISSN
0018-2052
2433-7668
NCID
出版者DOI
言語
英語
NII資源タイプ
紀要論文
広大資料タイプ
学内刊行物(紀要等)
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
権利情報
Copyright (c) 2020 Hiroshima University Medical Press
関連情報URL
部局名
医系科学研究科
病院
原爆放射線医科学研究所
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