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ID 34973
本文ファイル
著者
Kitahara, Yoshihiro
Hattori, Noboru
Yokoyama, Akihito
Inamizu, Tsutomu
キーワード
Exercise capacity
Lung function
%FEV1
Type 2 diabetes
NDC
医学
抄録(英)
Patients with type 2 diabetes have impaired exercise capacity. While numerous factors are known to contribute to impaired exercise capacity, the role of lung function remains unclear. We conducted the present study to investigate the influence of lung function on exercise capacity in patients with type 2 diabetes.

Cardiopulmonary exercise testing was carried out in 31 male patients with type 2 diabetes without diabetic complications or cardiopulmonary diseases. Patients with abnormal spirometry results such as a percentage of predicted forced vital capacity (%FVC) < 80% and/or a ratio of forced expiratory volume in one second (FEV1) to FVC (FEV1/FVC) < 70% were excluded from the study. We used the percentage of predicted maximal oxygen uptake (%V02max) as an index of exercise capacity. The correlations between %V02max and lung function and other factors known to be associated with impaired exercise capacity were then assessed.

Univariate analysis revealed % V02max correlated significantly with percentage of predicted FEV1 (%FEV1), duration of type 2 diabetes, regular exercise habits, and systolic and diastolic blood pressures. In a multivariate analysis, %FEV 1 and regular exercise habits were found to be independent determinants of% V02max.

A mild reduction in %FEV 1, which may be a complication of diabetes, is associated with impaired exercise capacity in patients with type 2 diabetes. When evaluating spirometric values in patients with type 2 diabetes, a reduction in %FEV1 should be noted even when both %FVC and FEV 1/FVC are within normal limits.
掲載誌名
Hiroshima Journal of Medical Sciences
59巻
1号
開始ページ
7
終了ページ
13
出版年月日
2010-03
出版者
Hiroshima University Medical Press
ISSN
0018-2052
NCID
言語
英語
NII資源タイプ
紀要論文
広大資料タイプ
学内刊行物(紀要等)
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
権利情報
(c) Hiroshima University Medical Press.
部局名
医歯薬学総合研究科
保健学研究科
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