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ID 49943
本文ファイル
著者
SANDA, Noriaki
NAKANO, Hiroshi
MIYAKE, Yoichiro
SUGINAKA, Hidekazu
NIHIRA, Hiromi
キーワード
Penicillin
Antibiotic resistance
Urinary tract infection
Pseudomonas aeruginosa
NDC
医学
抄録(英)
One hundred and thirteen clinical isolates of Pseudomonas aeruginosa from urinary tract infections were tested for their mechanisms of resistance to penicillins. Ninety-eight percent and 100.0% of the strains were resistant (MIC≧100 μg/ml) to ampicillin and penicillin G, respectively, while only 5.3% were resistant to piperacillin. Low permeability of the outer membrane, and penicillinase production were involved in their resistance mechanisms. Peptidoglycan synthesis in ether-treated cells of two representative strains was inhibited by ampicillin and piperacillin at the concentrations markedly lower than that for penicillin G.
掲載誌名
Hiroshima Journal of Medical Sciences
35巻
4号
開始ページ
355
終了ページ
362
出版年月日
1986-12
出版者
Hiroshima University School of Medicine
ISSN
0018-2052
NCID
PubMedID
言語
英語
NII資源タイプ
紀要論文
広大資料タイプ
学内刊行物(紀要等)
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
部局名
医歯薬学総合研究科
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