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ID 49947
本文ファイル
著者
SAITOH, Hitoshi
MUNEOKA, Yojiro
キーワード
Crustacean peptide
Inhibitory action
Mytilus muscle
NDC
医学
抄録(英)
It has been suggested that a peptide which belongs to the family of the arthropod neuropeptides, red pigment concentrating hormone (RPCH) and adipokinetic hormone (AKH), is also present in mollusc. In the present study, the effects of RPCH and AKH on the anterior byssus retractor muscle (ABRM), the pedal retractor muscle (PRM) and the heart of a bivalve, Mytilus edulis, were examined.
In most of the ABRMs examined, RPCH inhibited contractile response or catch-relaxing response or both, which were evoked by repetitive electrical pulses of stimulation. The threshold concentrations for the inhibition of contraction and relaxation were about 10^-7 M and 10^-8 M, respectively. In some of the muscles, however, both of the inhibitory effects or one of them was not found at 10^-6 M or less.
In most of the PRMs examined, RPCH also inhibited contractile response to repetitive electrical stimulation at 3 x 10^-8 M or higher, but in some of the muscles, it did not show the inhibitory effect at 3 x 10^-7 M.
Rhythmic activity in some hearts was inhibited by 10^-7 M or higher RPCH, but in the other hearts, the activity was not affected at 3 x 10^-6 M or was enhanced at 10^-6 M or higher.
AKH was found to be ineffective at 10^-6 M in all of the muscles of three kinds.
掲載誌名
Hiroshima Journal of Medical Sciences
35巻
4号
開始ページ
389
終了ページ
395
出版年月日
1986-12
出版者
Hiroshima University School of Medicine
ISSN
0018-2052
NCID
PubMedID
言語
英語
NII資源タイプ
紀要論文
広大資料タイプ
学内刊行物(紀要等)
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
部局名
医歯薬学総合研究科
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