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ID 49946
本文ファイル
著者
TAKEMOTO, Mayumi
SAITOH, Hitoshi
MUNEOKA, Yojiro
キーワード
FMRFamide analog
Relaxation
Catch muscle
NDC
医学
抄録(英)
In the anterior byssus retractor muscle (ABRM) of Mytilus, low concentrations of the molluscan neuropeptide Phe-Met-Arg-Phe-NH2 (FMRFamide) relax ACh-induced catch tension, whereas high concentrations cause contraction. In the present studies the actions of a FMRFamide-analog Trp-Nle-Arg-Phe-NH2 (W-Nle-RFamide) on the ABRM were investigated in order to compare them with those of FMRFamide.
The actions of W-Nle-RFamide were qualitatively similar to those of FMRFamide, but catch-relaxing activity of the former peptide was found to be 10-30 times more potent than that of the latter.
Cytochemical studies showed that FMRFamide-like immunoreactivity was localized to nerve branches in the ABRM and also to neurons in the pedal ganglion.
A peptide which structurally resembles FMRFamide may be involved in the mechanism of the control of relaxation of catch tension in the ABRM of Mytilus.
掲載誌名
Hiroshima Journal of Medical Sciences
35巻
4号
開始ページ
381
終了ページ
388
出版年月日
1986-12
出版者
Hiroshima University School of Medicine
ISSN
0018-2052
NCID
PubMedID
言語
英語
NII資源タイプ
紀要論文
広大資料タイプ
学内刊行物(紀要等)
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
部局名
医歯薬学総合研究科
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