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ID 49910
本文ファイル
著者
YAMAKIDO, Michio
YANAGIDA, Jitsuro
ISHIOKA, Shinichi
MATSUZAKA, Shigeru
HOZAWA, Soichiro
TAKAISHI, Masatoshi
INAMIZU, Tsutomu
AKIYAMA, Mitoshi
NISHIMOTO, Yukio
キーワード
Poison gas workers
Serum factors
Mitogenic response of lymphocytes
NDC
医学
抄録(英)
The relation of depressed immune function to carcinogenesis has been estimated in the living body. The authors have measured the immunological parameters in former poison gas workers, a group having a high risk of carcinogenesis, for comparison with age matched normal controls and the following results were obtained.
1) With regard to serum factors, no significant difference could be demonstrated between normal controls and poison gas workers in such immunoglobulins as IgG, IgA, and IgM, in acute phase reactants such as α1-AT, α1-AG, α2-HS and C3 and in such tumor markers as CEA, ferritin, and β2-microglobulin. Furthermore, no difference could be observed in the positive rate of immune complex and in complement activity.
2) No difference could be observed between the two groups with regard to tuberculin skin reaction and number of lymphocytes, but the longer the duration of work at the poison gas factory, the more significant was the increase in those who showed negative tuberculin skin reaction.
3) In comparison with normal controls, mitogenic response to PHA showed a significant decrease in poison gas workers, but no significant difference could be seen in mitogenic response to Con A and PPD and in mixed lymphocyte reaction.
4) No significant difference could be demonstrated between the two groups in the inhibitory effects of serum on mitogenic response to PHA and Con A and on mixed lymphocyte reaction.
掲載誌名
Hiroshima Journal of Medical Sciences
35巻
2号
開始ページ
117
終了ページ
126
出版年月日
1986-06
出版者
Hiroshima University School of Medicine
ISSN
0018-2052
NCID
PubMedID
言語
英語
NII資源タイプ
紀要論文
広大資料タイプ
学内刊行物(紀要等)
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
部局名
医歯薬学総合研究科
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