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ID 105
本文ファイル
著者
Cirelli, J.A.
Giannobile, William V.
キーワード
gene therapy
growth factors
tissue engineering
periodontal regeneration
regenerative medicine
NDC
医学
抄録(英)
Although significant advancements have been achieved in periodontal therapy over the last decade, predictable regeneration of the tooth-supporting tissues is a challenge in periodontology and oral implantology. Recently, gene therapy, a new therapeutic approach for genetic and acquired diseases, has been applied for tissue bioengineering in multiple clinical situations, including the craniofacial complex, among them defects resulting from periodontal disease. The use of gene therapy vectors has enhanced the bioavailability and targeting of multiple growth and host immune factors to repair alveolar bone defects. Early pre-clinical studies utilizing both ex vivo and in vivo gene transfer strategies demonstrate the feasibility of using gene therapy for periodontal tissue engineering. This review highlights the current progress made in the field of periodontal regenerative medicine via gene targeting approaches.
掲載誌名
Hiroshima Conference on Education and Science in Dentistry, 2006 : the 40th Anniversary of Hiroshima University Faculty of Dentistry
開始ページ
120
終了ページ
125
出版年月日
2006-01-08
言語
英語
NII資源タイプ
会議発表論文
広大資料タイプ
会議発表論文
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
関連情報URL(isPartOf)
http://ir.lib.hiroshima-u.ac.jp/00014842
部局名
医歯薬学総合研究科