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ID 48707
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著者
Matsubara, Hiroki 大学院工学研究科
Hirano, Hiroki 大学院工学研究科
Hirano, Harutoyo
Soh, Zu 大学院工学研究科 広大研究者総覧
Nakamura, Ryuji 大学院医歯薬保健学研究科
Saeki, Noboru 大学院医歯薬保健学研究科 広大研究者総覧
Kawamoto, Masashi 大学院医歯薬保健学研究科(医)
Yoshizumi, Masao 大学院医歯薬保健学研究科(医) 広大研究者総覧
Yoshino, Atsuo 大学院医歯薬保健学研究科(医)
Yamawaki, Shigeto 大学院医歯薬保健学研究科(医) 広大研究者総覧
Tsuji, Toshio 大学院工学研究科 広大研究者総覧
抄録(英)
In clinical practice, subjective pain evaluations, e.g., the visual analogue scale and the numeric rating scale, are generally employed, but these are limited in terms of their ability to detect inaccurate reports, and are unsuitable for use in anesthetized patients or those with dementia. We focused on the peripheral sympathetic nerve activity that responds to pain, and propose a method for evaluating pain sensation, including intensity, sharpness, and dullness, using the arterial stiffness index. In the experiment, electrocardiogram, blood pressure, and photoplethysmograms were obtained, and an arterial viscoelastic model was applied to estimate arterial stiffness. The relationships among the stiffness index, self-reported pain sensation, and electrocutaneous stimuli were examined and modelled. The relationship between the stiffness index and pain sensation could be modelled using a sigmoid function with high determination coefficients, where R2 ≥ 0.88, p < 0.01 for intensity, R2 ≥ 0.89, p < 0.01 for sharpness, and R2 ≥ 0.84, p < 0.01 for dullness when the stimuli could appropriately evoke dull pain.
内容記述
This work was supported by the Center of Innovation Program from Japan Science and Technology Agency.
Supplementary information accompanies this paper at https://doi.org/10.1038/s41598-018-21223-1.
掲載誌名
Scientific Reports
8巻
開始ページ
3091
出版年月日
2018-02-15
出版者
Nature Research
ISSN
2045-2322
出版者DOI
言語
英語
NII資源タイプ
学術雑誌論文
広大資料タイプ
学術雑誌論文
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application/pdf
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© The Author(s) 2018. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
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工学研究科
医歯薬保健学研究科
その他