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ID 35026
本文ファイル
著者
Ikeda, Hiromi
Ishizaki, Fumiko
Harada, Toshihide
Aoi, Satomi
Iida, Tadayuki
Tamura, Noriko
Chikamura, Chiho
Nitta, Yumiko
Nitta, Kohsaku
キーワード
Glycometabolism
TDAS
HDS-R
Mild cognitive impairment
NDC
医学
抄録(英)
There is a suspected relationship between glycometabolism and cognitive function in nondiabetic women. In this study, we aimed to give further evidence of a correlation between glycometabolism and cognitive function with the use of a new computer-based rating scale for Alzheimer's disease, TDAS. The subjects were 174 non-diabetic, middle-aged, older women. The levels of hemoglobin A1c (HbA1c, the Japan Diabetes Society (JDS)), TDAS and Revised Hasegawa's Dementia Rating Scale (HDS-R) were measured. Mean value of HbA1c, score of TDAS, time of TDAS and HDS-R were 5.2 ± 0.3 (n = 169), 0.9 ± 1.4 n = 173), 13.0 ± 1.4 min (n = 173) and 29.4 ± 1.0 (n = 174), respectively. The coefficient of the correlation (r) between age and HbA1c was 0.31, that between age and HDS-R was -0.21, that between age and score of TDAS was 0.33, and that between age and time of TDAS was 0.43. The correlations were significant. There was no correlation between HbA1c and HDS-R. The coefficient of the correlation (r) between HbA1c and score of TDAS was 0.16 (p = 0.042), and that between HbA1c and time of TDAS was 0.17 (p =0.027). The correlations between HbA1c and score of TDAS and between HbA1c and time of TDAS were significant.

These results suggest that TDAS is very useful for evaluation of cognitive function and that there is a correlation between glycometabolism and cognitive function in non-diabetic middleaged and older women, even if their cognitive function is within normal limits.
掲載誌名
Hiroshima Journal of Medical Sciences
62巻
2号
開始ページ
27
終了ページ
30
出版年月日
2013-06
出版者
Hiroshima University Medical Press
ISSN
0018-2052
NCID
言語
英語
NII資源タイプ
紀要論文
広大資料タイプ
学内刊行物(紀要等)
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
権利情報
(c) Hiroshima University Medical Press.
部局名
医歯薬保健学研究科
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