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ID 35025
本文ファイル
著者
Han, Yanbai
Wang, Hongli
キーワード
Leptin
Anthropometry
Metabolic syndrome
Postmenopausal
NDC
医学
抄録(英)
Postmenopausal women gain abdominal and visceral fat during the menopausal period. Leptin is an adipocyte-secreted hormone that is involved in metabolic disturbance disease. However, few studies have investigated the associations between leptin and metabolic syndrome (MS) in Chinese postmenopausal women. The purpose of this study was to examine the relationships of serum leptin and anthropometry, physical work capacity and MS in sixty Chinese postmenopausal women. Factor analysis extracted five factors characterized by leptin and obesity, muscle mass and physical work capacity, blood pressure and atherosclerosis, cardiovascular risk marker, and cholesterol, which accounted for 78.38% of the total variance. Leptin correlated positively with waist-to-hip ratio, body mass index and systolic blood pressure, and correlated negatively with physical work capacity of 75% heart rate max (R2 = 0.805, p < 0.001). Leptin levels in MS subjects with central obesity were higher than in both non-MS subjects (p < 0.01) and MS subjects without central obesity (p < 0.05). Subjects with a high leptin level had higher risks of the development of MS with central obesity than non-MS subjects (OR = 16.00, 95% confidence interval (CI): 3.15-51.26, p < 0.01), and MS subjects without central obesity (OR = 16.00, 95% CI: 1.69-81.53, p < 0.05). In conclusion, serum leptin can be predicted by waist-to-hip ratio, BMI, physical work capacity, and systolic blood pressure. In addition, a high leptin level increases the risk of MS with central obesity.
掲載誌名
Hiroshima Journal of Medical Sciences
62巻
2号
開始ページ
21
終了ページ
26
出版年月日
2013-06
出版者
Hiroshima University Medical Press
ISSN
0018-2052
NCID
言語
英語
NII資源タイプ
紀要論文
広大資料タイプ
学内刊行物(紀要等)
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
権利情報
(c) Hiroshima University Medical Press.
部局名
医歯薬保健学研究科
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