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ID 46202
本文ファイル
著者
Ikeda, Atsushi 大学院工学研究科 広大研究者総覧
Funada, Rikushi
Sugikawa, Kouta 大学院工学研究科 広大研究者総覧
NDC
化学
抄録(英)
Liposomes composed of unsaturated lipids were more stable than those containing saturated lipids toward DMe‐β‐CDx, DMe‐α‐CDx and DMe‐β‐CDx. The Hill coefficient values (n) indicated that the saturated lipid•DMe‐CDx complexes had stoichiometric ratios in the range of 1:3‒1:4, while the unsaturated lipid•DMe‐CDx complexes had ratios in the range of 1:1.5‒1:3. That is, a cis alkene group in the unsaturated lipids prevented complexation with a second DMe‐CDx in the direction toward each acyl chain. Furthermore, the liposomes composed of the unsaturated lipids were much slower to form precipitates upon the addition of α‐CDx than those of the saturated lipids. To the best of our knowledge, this is the first example showing that CDxs interact with unsaturated lipids.
内容記述
This work was supported by the Japanese Society for the Promotion of Science (JSPS) KAKENHI a Grant‐in‐Aid for Scientific Research (B) (Grant No. 25288037 and No. 16H04133) and a Grant‐in‐Aid for Challenging Exploratory Research (Grant No. 16K13982).
掲載誌名
Organic and Biomolecular Chemistry
14巻
22号
開始ページ
5065
終了ページ
5072
出版年月日
2016-06-04
出版者
Royal Society of Chemistry
ISSN
1477-0520
出版者DOI
PubMedID
言語
英語
NII資源タイプ
学術雑誌論文
広大資料タイプ
学術雑誌論文
DCMIタイプ
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application/pdf
著者版フラグ
author
権利情報
Copyright (c) 2016 The Royal Society of Chemistry
This is not the published version. Please cite only the published version. この論文は出版社版でありません。引用の際には出版社版をご確認ご利用ください。
部局名
工学研究科