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ID 51386
本文ファイル
著者
SHIMOMURA, Manabu
SHIMADA, Yuko
TOYOTA, Kazuhiro
EGI, Hiroyuki 大学院医系科学研究科(医)
OHDAN, Hideki 大学院医系科学研究科(医) 広大研究者総覧
TAKAHASHI, Tadateru
キーワード
Chemotherapy-induced nausea and vomiting
Multinational Association of Supportive Care in Cancer Antiemesis Tool
Colorectal cancer
抄録(英)
This study aimed to evaluate the frequency and extent of chemotherapy-induced nausea and vomiting (CINV) in patients with colorectal cancer (CRC) who underwent chemotherapy, using the Multinational Association of Supportive Care in Cancer (MASCC) Antiemesis Tool (MAT), and establish an antiemetic protocol for the management of CINV, independent of the treating oncologist. We conducted a prospective observational study from October 2017 to June 2018 at the Higashihiroshima Medical Center. Patients who had undergone moderate CINV risk chemotherapy for CRC were eligible. The incidence of CINV was evaluated using the MAT, and medical prophylaxis was gradually provided following the antiemetic protocol. We enrolled 30 patients, and 27 of 30 patients (90%) were assessed more than once using the MAT. Among these 27 patients, the incidence of acute nausea was 30% and delayed nausea was 26% as evaluated using the MAT based on recommended pharmacological prophylaxis guidelines. Between the start and end of the survey, there was no significant difference in the numeric rating scale (NRS) score for acute nausea, but there was a significant reduction in the NRS score for delayed nausea. The clinical significance of the antiemetic protocol as assessed using the MAT in reducing CINV was demonstrated. The clinical use of the protocol may help in the realization that selective pharmacological prophylaxis for patients with CINV is possible, independent of the treating oncologist.
掲載誌名
Hiroshima Journal of Medical Sciences
70巻
1号
開始ページ
1
終了ページ
5
出版年月日
2021-06-30
出版者
Hiroshima University Medical Press
ISSN
0018-2052
2433-7668
NCID
出版者DOI
言語
英語
NII資源タイプ
紀要論文
広大資料タイプ
学内刊行物(紀要等)
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
権利情報
Copyright (c) 2021 Hiroshima University Medical Press
関連情報URL
部局名
医系科学研究科
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