Pemphigus Vulgaris with Marked Stenosis of the Esophageal Orifice from an Osteoporosis Drug: a Case Study with Long-term Follow-up
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ID | 44646 |
本文ファイル | |
著者 |
Ishibashi, Takuya
病院(医)
Hirakawa, Katsuhiro
医療政策室
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キーワード | Pemphigus Vulgaris
Stenosis of esophageal orifice
Osteoporosis drug
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NDC |
医学
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抄録(英) | Pemphigus vulgaris produces multiple and intractable erosions of the oral mucosa in the head and neck region. We describe a case of pemphigus vulgaris that showed erosions in the hypopharynx and stenosis of the esophageal orifice from an osteoporosis drug. A 73-year-old woman was admitted with oral intake difficulty and erosions in the hypopharynx. During the first admission, we could not make a definite diagnosis by biopsy or blood examination. The condition of the mucosa worsened subsequently; an esophagram showed marked stenosis of the esophageal orifice. As a possible factor exacerbating the stenosis, an osteoporosis drug was considered. The stenosis was improved by balloon expansion. One year after the first medical examination, we finally made a definite diagnosis of pemphigus vulgaris from the results of a blood examination in which anti-desmoglein 3 turned positive when the hypopharyngeal erosions and stenosis of the esophageal orifice became worse. Systemic treatment with a steroid was effective for the control of pemphigus vulgaris; restenosis of the esophageal orifice was recognized twice during a state of remission, and careful follow-up will be necessary in the future.
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掲載誌名 |
Hiroshima Journal of Medical Sciences
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巻 | 66巻
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号 | 2号
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開始ページ | 27
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終了ページ | 30
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出版年月日 | 2017-08
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出版者 | Hiroshima University Medical Press
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ISSN | 0018-2052
2433-7668
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NCID | |
出版者DOI | |
言語 |
英語
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NII資源タイプ |
紀要論文
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広大資料タイプ |
学内刊行物(紀要等)
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DCMIタイプ | text
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フォーマット | application/pdf
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著者版フラグ | publisher
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権利情報 | Copyright (c) 2017 Hiroshima University Medical Press
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関連情報URL | |
部局名 |
医歯薬保健学研究科
病院
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他の一覧 |