A First Case of Hepatic Angiosarcoma Treated with Recombinant Interleukin-2
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ID | 35003 |
本文ファイル | |
著者 |
Mitsui, Fukiko
Hashimoto, Yoshimasa
Katamura, Yoshio
Takaki, Shintaro
Waki, Koji
Takahashi, Shoichi
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キーワード | Hepatic angiosarcoma
Recombinant interleukin-2
Hepatic arterial infusion therapy
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NDC |
医学
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抄録(英) | A 60 year-old woman was admitted to our hospital because of management of multiple liver tumors. According to image findings and liver biopsy, she was diagnosed as having epithelioid hemangioendothelioma of the liver accompanied by metastases in the spleen, lungs and bones. Based on the spread of the liver tumors and the extensive systemic metastases, she was considered inoperable. Instead, she received hepatic arterial infusion therapy using recombinant interleukin-2. However, she died due to liver failure about two months after admission. Autopsy revealed that the liver tumor was angiosarcoma. It is difficult to differentiate angiosarcoma from epithelioid hemangioendothelioma based on the image findings and pathological findings of percutaneous liver biopsy. Many cases are diagnosed as angiosarcoma at autopsy. There is no established effective treatment for hepatic angiosarcoma, because the tumor stage at the time of diagnosis is often progressive. To date, immunotherapy with recombinant interleukin-2 has been reported to be effective clinically for cutaneous angiosarcoma, such as of the scalp and facial skin. To our knowledge, there have been no reported cases of hepatic angiosarcoma treated with recombinant interleukin-2. Our case is important should recombinant interleukin-2 be considered effective for hepatic angiosarcoma in the future.
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掲載誌名 |
Hiroshima Journal of Medical Sciences
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巻 | 60巻
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号 | 4号
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開始ページ | 91
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終了ページ | 96
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出版年月日 | 2011-12
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出版者 | Hiroshima University Medical Press
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ISSN | 0018-2052
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NCID | |
言語 |
英語
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NII資源タイプ |
紀要論文
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広大資料タイプ |
学内刊行物(紀要等)
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DCMIタイプ | text
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フォーマット | application/pdf
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著者版フラグ | publisher
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権利情報 | (c) Hiroshima University Medical Press.
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部局名 |
医歯薬学総合研究科
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他の一覧 |