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ID 38138
本文ファイル
著者
Eto, Ryozo
Ishimaru, Toranosuke
Tokunaga, Masayoshi
キーワード
Urinary bladder
Dysplasia
Hyperplasia
Atomic bomb survivors
NDC
医学
抄録(英)
From the ABCC-RERF Life Span Study extended sample, there were 4,499 cases in the Pathology Study sample of atomic bomb survivors who had come to autopsy in the period 1960-83. Among 370 subjects who were heavily exposed with an estimated dose (T65D) of 100 rad or more, 72 (about 20%) of them, whose urinary bladder epithelia had been preserved satisfactorily to suit the purpose of this study, were sampled as the index group. An equal number of control subjects were selected from the unexposed group individually, matched with the index cases by city, sex, age at death, and year of death. However, cases with marked epithelial autolysis and those pathologically diagnosed as urinary bladder cancer were previously excluded from both the index group and control subjects. These 72 pairs of autopsy cases were pathologically studied for the presence or absence of epithelial lesions of the urinary bladder, namely, hyperplasia, dysplasia and carcinoma-in-situ, and the frequencies of appearance of these lesions were compared statistically by X2 test based on a case-control study design.

Carcinoma-in-situ and severe dysplasia were detected in neither the index cases nor the control cases. The risk was relatively higher in the index group than in the control subjects for both hyperplasia and dysplasia (mild and moderate), in particular the relative risk of papillary hyperplasia being about 4.0, but as the total number of cases were small, this was not statistically significant.
掲載誌名
Hiroshima Journal of Medical Sciences
37巻
1号
開始ページ
11
終了ページ
15
出版年月日
1988-03
出版者
Hiroshima University Medical Press
ISSN
0018-2052
NCID
PubMedID
言語
英語
NII資源タイプ
紀要論文
広大資料タイプ
学内刊行物(紀要等)
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
部局名
医歯薬学総合研究科
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