このエントリーをはてなブックマークに追加
ID 49902
本文ファイル
著者
NAKANISHI, Masanao
キーワード
Mycobacterium lepraemurium
M. Intracellulare
Vaccination
NDC
医学
抄録(英)
Since Mycobacterium lepraemurium (Mlm) is closely related to Mycobacterium intracellulare, with respect to its antigenicity, attenuated Mlm obtained by passages on 1% Ogawa egg medium was examined for possible effects as a vaccine against M. intracelJulare infection. Four weeks after subcutaneous injection of Mlm (1.4 x 107 bacilli), mice were infected intravenously with 2.4 x 107 organisms per mouse of M. intracellulare. During the first 12 weeks, no difference was noted in the rate of progression of M. intracellulare infection between mice given or not given Mlm-vaccine, when severity of the infection was measured on the basis of the number of viable M. intracellulare in the lungs and spleen. Therefore, Mlm-vaccine is probably not efficacious in protecting mice against M. intracellulare infection.
掲載誌名
Hiroshima Journal of Medical Sciences
35巻
1号
開始ページ
67
終了ページ
69
出版年月日
1986-03
出版者
Hiroshima University School of Medicine
ISSN
0018-2052
NCID
PubMedID
言語
英語
NII資源タイプ
紀要論文
広大資料タイプ
学内刊行物(紀要等)
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
部局名
医歯薬学総合研究科
他の一覧