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ID 49892
本文ファイル
著者
HORIKAWA, Yoshiya
キーワード
Lactobacillus casei ointment
Thermal injury
Opportunistic infection
NDC
医学
抄録(英)
I studied the effects of LC ointment made of Solbase and heat-killed Lactobacillus casei YIT 0003 on the healing of thermal injury wounds and the elimination of bacteria from infected wounds in mice. LC ointment promoted the healing of the uninfected thermal injury wounds and thermal injury wounds infected with Pseudomonas aeruginosa alone or with mixed bacterial suspension of Staphylococcus aureus, Escherichia coli and P. aeruginosa and resulted in the elimination of infecting bacteria. Histopathologically, the formation of collagen fibers in wounded subcutaneous tissues to which LC ointment was applied was more remarkable than that of tissues treated with Solbase (ointment base). The clearance of bacteria and promotion of healing of the infected thermal injury wounds due to LC ointment were superior to those of Eksalb ointment, Azunol ointment and Mafatate (mafenide acetate) cream, and almost the same degree as that of Geben (silver sulfadiazine) cream. These effects of L. casei were nearly the same or somewhat superior compared with that of other lactobacilli, and were enhanced by the addition of gentamicin or ofloxacin.
掲載誌名
Hiroshima Journal of Medical Sciences
35巻
1号
開始ページ
1
終了ページ
14
出版年月日
1986-03
出版者
Hiroshima University School of Medicine
ISSN
0018-2052
NCID
PubMedID
言語
英語
NII資源タイプ
紀要論文
広大資料タイプ
学内刊行物(紀要等)
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
部局名
医歯薬学総合研究科
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