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ID 49162
本文ファイル
著者
Jinnin, Ran 大学院医歯薬保健学研究科(医) 広大研究者総覧
Okamoto, Yasumasa 大学院医歯薬保健学研究院 広大研究者総覧
Takagaki, Koki 保健管理センター 広大研究者総覧
Nishiyama, Yoshiko
Yamamura, Takanao
Okamoto, Yuri 保健管理センター 広大研究者総覧
Miyake, Yoshie 保健管理センター 広大研究者総覧
Takebayashi, Yoshitake
Tanaka, Keisuke
Sugiura, Yoshinori 大学院総合科学研究科 広大研究者総覧
Shimoda, Haruki
Kawakami, Norito
Furukawa, Toshi A
Yamawaki, Shigeto 大学院医歯薬保健学研究院 広大研究者総覧
キーワード
adolescence
subthreshold depression
major depressive episode
university student
cohort study
抄録(英)
Purpose: Despite its clinical importance, adolescent subthreshold depression remains a largely neglected topic. The aims of this study were to accurately identify the natural course of depressive symptoms and the risk for developing major depressive episode (MDE) in late adolescents with subthreshold depression over 1 year.
Patients and methods: One hundred and seventy-two participants <20 years of age (mean age: 18.32 years, standard deviation: 0.50), who did not meet the full criteria for an MDE, were selected from 2,494 screened freshmen based on the Beck Depression Inventory, 2nd edition (BDI-II). We conducted a cohort study of three groups (low-, middle-, and high-symptom groups) divided based on BDI-II scores, over a 1 year period with the use of bimonthly assessments. Temporal changes of depressive symptoms were analyzed using linear mixed modeling and growth mixture modeling.
Results: First, we found that late adolescents with subthreshold depression (high depressive symptoms) were split between the increasing and decreasing depressive symptoms groups, whereas the majority of the less-symptoms group remained stable during 1 year. Second, in comparison with late adolescents with less depressive symptoms, those with subthreshold depression had an elevated risk of later depression.
Conclusion: Some late adolescents with subthreshold depression had increased depressive symptoms and developed an MDE during 1 year. Therefore, it is necessary for us to rigorously assess the changes in subthreshold depressive symptoms over time in late adolescents.
内容記述
This study was supported (in part) by JSPS KAKENHI Grant Number JP16H06395, JP16H06399 and Grant-in-Aid for Scientific Research on Innovative Areas (23118004; Adolescent Mind & Self-Regulation) from the Ministry of Education, Culture, Sports, Science and Technology.
掲載誌名
Neuropsychiatric Disease and Treatment
13巻
開始ページ
25
終了ページ
33
出版年月日
2016-12-22
出版者
Dove Medical Press
ISSN
1176-6328
1178-2021
出版者DOI
PubMedID
言語
英語
NII資源タイプ
学術雑誌論文
広大資料タイプ
学内刊行物(紀要等)
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
権利情報
© 2017 Jinnin et al. This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
関連情報URL
部局名
総合科学研究科
医歯薬保健学研究科
保健管理センター