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ID 20324
本文ファイル
著者
Nishimura, Haruki
Makihira, Seicho
Hamada, Taizo
Sadamori, Shinsuke
Samaranayake, Lakshman P.
抄録(英)
The biofilm formation of the oral fungal pathogen Candida on denture acrylic strips coated with saliva, serum and, saliva/serum pellicle were examined in vitro using C. albicans (4 isolates), C. glabrata (3 isolates) and C. tropicalis (3 isolates). The degree of biofilm activity varied depending upon both the isolate and the pellicle. Thus as compared with the uncoated control, significantly increased biofilm activity on the pellicle (particularly serum)-coated strips, was observed with three isolates of C. albicans and another of C. glabrata on protein coated acrylics, with increasing concentration of serum in the pellicle (ANOVA; p<0.01). Similar trends were observed with one isolate ofC albicans and C. grabrata, though the effects of pellicles were not significant (ANOVA; p>0.05). In contrast, with all 3 isolates of C. tropicalis and a single isolate of C. glabrata, although the biofilm activity on the protein-free control strips was significantly higher than that of saliva-coated strips, the activity of pellicle admixed-biofilm was increased depending upon the serum-concentration. Taken together our in vitro findings that candidal biofilm formation on acrylic surfaces is essentially promoted with increase in the concentration of serum in pellicle, suggest that inflamation in the oral environment would facilitate the fungal colonization on denture acrylic.
掲載誌名
Mycoses
43巻
3-4号
開始ページ
139
終了ページ
143
出版年月日
2000
出版者
Blackwell Publishing
ISSN
0019-3879
NCID
出版者DOI
PubMedID
言語
英語
NII資源タイプ
学術雑誌論文
広大資料タイプ
学術雑誌論文
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
author
権利情報
Copyright (c) 2000 Blackwell Publishing. The definitive version is available at www.blackwell-synergy.com
関連情報URL
部局名
医歯薬学総合研究科