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ID 19896
本文ファイル
著者
Kawasaki, Ayako
Sagata, Noriyuki
キーワード
Xenopus
oogenesis
cell-cycle regulator
抄録(英)
In full-grown Xenopus oocytes, cell-cycle regulators and an inactive form of maturation/M phase promoting factor (pre-MPF) are stored ready to bring about a specific cell cycle for oocyte maturation. We examined the expression pattern of these cell-cycle regulators as well as pre-MPF formation during oogenesis. Cdc2 and Cyclin B2 were already present in stage I oocytes and pre-MPF formation was also detected in stage I oocytes. Some negative regulators of MPF, Myt1 and Chk1, were synthesized early in oogenesis. In contrast, positive regulators of MPF, MEK, MAPK and Cdc25C, were mainly synthesized late in oogenesis. Northern blotting analysis suggested that the synthesis of these cell-cycle regulators was controlled by translation.
掲載誌名
Gene Expression Patterns
3巻
2号
開始ページ
165
終了ページ
168
出版年月日
2003-05
出版者
Elsevier Science B.V.
ISSN
1567-133X
NCID
出版者DOI
言語
英語
NII資源タイプ
学術雑誌論文
広大資料タイプ
学術雑誌論文
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
author
権利情報
Copyright (c) 2003 Elsevier Science B.V.
関連情報URL(IsVersionOf)
http://dx.doi.org/10.1016/S1567-133X(03)00037-1
部局名
理学研究科