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ID 26281
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別タイトル
Possible factors contributing to muscle fatigue during intense exercise : effects of inorganic phosphate, glycogen and reactive oxygen species
著者
坂本 誠
杉山 美奈子
松永 智
キーワード
sarcoplasmic reticulum
Ca2+ release channel
oxidative stress
myofibril
excitation-contraction coupling
筋小胞体
Ca2+放出チャンネル
酸化ストレス
筋原線維
興奮収縮連関
NDC
スポーツ・体育
抄録(英)
Skeletal muscles induced to contract repeatedly respond with a progressive loss in their ability to generate a target force or power. This decline in function, referred to as muscle fatigue, has a complex etiology that can involve various metabolic and ionic factors. Of these, intracellular acidosis due to lactic acid accumulation has been regarded as one of the important causes of muscle fatigue that occurs with intense exercise. Recent surveys, however, have demonstrated little direct effect of acidosis on muscle function at physiological temperatures, and in fact several putative mechanisms by which intracellular changes can attenuate contractile function have been proposed. The most likely mechanisms to explain muscle fatigue include elevated inorganic phosphate concentrations that result from phosphocreatine breakdown, compartmentalized depletion of endogenous muscle glycogen and/or modification by reactive oxygen species that are produced extensively in contracting muscle fibers. This brief review seeks to examine how these three alterations contribute to muscular fatigue processes.
内容記述
Japan J. Phys. Educ. Hlth. Sport Sci. 51: 399-408, July, 2006
掲載誌名
体育學研究
51巻
4号
開始ページ
399
終了ページ
408
出版年月日
2006-07-10
出版者
日本体育学会
ISSN
0484-6710
NCID
言語
日本語
NII資源タイプ
学術雑誌論文
広大資料タイプ
学術雑誌論文
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
権利情報
Copyright (c) 2006 日本体育学会
この論文の著作権は(社)日本体育学会に帰属します
部局名
総合科学研究科