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ID 26007
本文ファイル
別タイトル
EFFECT OF HIGH-INTENSITY TRAINING AND ACUTE EXERCISE ON Ca^<2+>-SEQUESTERING FUNCTION OF SARCOPLASMIC RETICULUM : ROLE OF OXIDATIVE MODIFICATION
著者
松永 智
三島 隆章
山田 崇史
キーワード
muscle fatigue
reactive oxygen species
Ca^<2+>-uptake
adaptation
NDC
医学
抄録(英)
To investigate the influences of high-intensity training and/or a single bout of exercise on in vitro Ca^<2+>-sequestering function of the sarcoplasmic reticulum (SR), the rats were subjected to 8 weeks of an interval running program (final training: 2.5-min running×4 sets per day, 50m/min at 10% incline). Following training, both trained and untrained rats were run at a 10% incline, 50 m/min for 2.5min or to exhaustion. SR Ca^<2+>-ATPase activity, SR Ca^<2+>-uptake rate and carbonyl group contents comprised in SR Ca^<2+>-ATPase activity were examined in the superficial portions of the gastrocnemius and vastus lateralis muscles. For rested muscles, a 12.7% elevation in the SR Ca^<2+>-uptake rate was induced by training. Training led to improved running performance (avg time to exhaustion: untrained-191.1 vs trained-270.9 sec; P<0.01). Regardless of training status, a single bout of exercise caused progressive reductions in SR Ca^<2+>-ATPase activity and SR Ca^<2+>-uptake rate. Increases in carbonyl content only occurred after exhaustive exercise (P<0.05). At both point of 2.5-min and exhaustion, no differences existed in SR Ca^<2+>-sequestering capacity and carbonyl content between untrained and trained muscles. These findings confirm the previous findings that oxidative modifications may account, at least partly, for exercise-induced deterioration in SR Ca^<2+>-sequestering function; and raise the possibility that in the final phase of acute exercise, high-intensity training could delay the progression of protein oxidation of SR Ca^<2+>-ATPase.
掲載誌名
体力科学 : Japanese Journal of Physical Fitness and Sports Medicine
57巻
3号
開始ページ
327
終了ページ
338
出版年月日
2008-06-01
出版者
日本体力医学会
ISSN
0039-906X
NCID
言語
日本語
NII資源タイプ
学術雑誌論文
広大資料タイプ
学術雑誌論文
DCMIタイプ
text
フォーマット
application/pdf
著者版フラグ
publisher
権利情報
日本体力医学会
本文データは学協会の許諾に基づきCiNiiから複製したものである
関連情報URL
部局名
総合科学研究科